Preconditioning and Shear Stress in the Microcirculation in Ischemia-Reperfusion InjuryĬurrent Cardiology Reviews Pleiotropic Effects of Statins - Clinical EvidenceĬurrent Pharmaceutical Design The Application of NMR Spectroscopy for the Study of Heart FailureĬurrent Pharmaceutical Design Macronutrient Specific Postprandial Oxidative Stress: Relevance to the Development of Insulin ResistanceĬurrent Diabetes Reviews Transmucosal Delivery of Linagliptin for the Treatment of Type- 2 Diabetes Mellitus by Ultra-Thin NanofibersĬurrent Drug Delivery Recent Applications of Grape Polyphenols in Foods, Beverages and Supplements Cardiovascular risk is best evaluated with an estimation that takes into account the individuals characteristics and risk factors. Nevertheless, the American Diabetes Association has recognized that absolute risk for cardiovascular disease varies among individuals with diabetes and has recommended the use of designed models and algorithms to estimate risk, especially in younger patients ( < 40 years). Diabetes itself has been considered a cardiovascular disease equivalent. The presence of traditional and nontraditional risk factors that frequently coexist with type 2 diabetes are associated with this higher cardiovascular risk. Mexico DF, Mexico.,IranĪbstract: Individuals with type 2 diabetes have a two to four fold increased risk for developing cardiovascular disease than persons without diabetes. Endocrinology and Metabolism Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Vasco de Quiroga No.
Title: UKPDS Risk Engine, Decode and Diabetes PHD Models for the Estimation of Cardiovascular Risk in Patients with DiabetesĪuthor(s): Paloma Almeda-Valdes, Daniel Cuevas-Ramos, Roopa Mehta, Francisco J. Keywords: Cardiovascular risk, Diabetes mellitus, UKPDS risk engine, Diabetes PHD, DECODE In this review we will discuss the pros and cons of each model, their use in clinical practice and the application of the UKPDS risk engine and PHD model in a Mexican population. Specifically, the DECODE (Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in Europe) equation has been shown to have discriminative capacity of 0.67 the UKPDS Risk Engine model is reported to have a sensitivity of around 90% and specificity of 33% and the Diabetes Personal Health Decisions (PHD) in our study had a sensitivity of 67% and specificity of 41%. The algorithms and models that have been designed specifically for the assessment of cardiovascular risk in individuals with diabetes will be the subject of this review.
Individuals with type 2 diabetes have a two to four fold increased risk for developing cardiovascular disease than persons without diabetes.
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